I have never made a handbag with a purse frame before, but I LOVE how it turned out. I referred to U-Handbag for resources in designing a bag around a purse frame. (Meowcraft is the only place I will buy purse frames, they are THE best!)
This is a mock-up for the diaper bag I am making for Lindsay. Mine is smaller, but the same shape I am planning for her bag. The front has a little puff-pouch to hold my phone, and the back has a quick-access pocket to throw keys or something. I love the blue, teal, and brown vintage print fabric.
I put a stiff divider in the center to make it more organized. I use this as a diaper bag for Eddie, as well as my purse. So now I can keep his stuff on one side (you can see the teal sippy cup holders, and his diapers/wipes fit perfect in between, with a pocket for his snacks), and my stuff on the other, (there is a pocket for my makeup, one for notebook/pens, one for my Palm, etc).